antigenic determinant
Học thuậtThân thiện
Definition
- Noun:
- The specific site on an antigen molecule: An "antigenic determinant" is the precise molecular region on the surface of an antigen where an antibody or a receptor on a lymphocyte binds. It is the part of the antigen that is recognized by the immune system.
Usage Examples
- Noun:
- The antibody's specificity is determined by its precise fit to the antigenic determinant.
- Scientists are mapping the antigenic determinant to develop a more targeted vaccine.
Advanced Usage
- "Epitope": This is a direct synonym for "antigenic determinant" and is the more commonly used term in modern immunology.
- The viral protein contains several critical epitopes that trigger an immune response.
Variants and Related Words
- Epitope (noun): A synonym for antigenic determinant.
- Paratope (noun): The site on an antibody that binds to the antigenic determinant (epitope).
- Antigen (noun): A substance that induces an immune response, often by containing multiple antigenic determinants.
Synonyms
- Epitope: The specific part of an antigen that is recognized.
- Antigenic site: A less technical term for the region on an antigen that is immunologically active.
Related Phrases
- Antigen-antibody binding: The interaction where an antibody attaches to an antigenic determinant.
- The strength of the antigen-antibody binding depends on the affinity for the antigenic determinant.
- B-cell receptor recognition: The process by which a B-cell identifies an antigen via its antigenic determinant.
- The first step in antibody production is B-cell receptor recognition of an antigenic determinant.
Noun
- the site on the surface of an antigen molecule to which an antibody attaches itself